OMIDRIA maintained pupil size by preventing intraoperative miosis1,6,17,18
Intraoperative Pupil Diameter
(mm) Change From Baseline
Intraoperative Pupil Constriction
at Any Time During the Procedure*†
|Pupil diameter <6 mm at lens implantation*||4.0%||22.7%||p<0.0001|
|≥2.5 mm pupillary constriction at any time during the procedure*||2.1%||27.1%||p<0.0001|
*This is a post hoc analysis of the full analysis data set. Pooled results from Study 1 and Study 2.
†p-values from Chi-square or Fisher's Exact test.
‡Subjects with missing or unreadable videos were excluded from these analyses.
OMIDRIA decreased postoperative ocular pain for 10 to 12 hours after surgery1,6,17,18
(VAS ≥40) at Any Time Point
Postoperative Mean Visual Analog Scale (VAS) Scores for Pain†
Two, randomized, multicenter, double-masked, placebo-controlled trials in 808 adult patients undergoing cataract surgery or intraocular lens replacement1,6,17
- All patients were treated preoperatively with topical mydriatic and anesthetic agents
- For purposes of standardization across clinical sites, no preoperative NSAID was administered
- All patients were allowed to take standard analgesics for postoperative pain
- Principal endpoints for both studies:
- Change in pupil diameter over time
- Patient-reported ocular pain in the early postoperative period